Isoniazid/rifampicin explained
| Type: | combo |
| Component1: | Isoniazid |
| Class1: | Anti-tuberculosis medication |
| Component2: | Rifampicin |
| Class2: | Anti-tuberculosis medication |
| Tradename: | IsonaRif, Rifamate, others |
| Pregnancy Us: | C |
| Cas Number: | 51683-28-4 |
| Atc Prefix: | J04 |
| Atc Suffix: | AM02 |
| Kegg: | D11578 |
Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis. It is a fixed dose combination of isoniazid and rifampicin (rifampin). It is used together with other antituberculosis medication. It is taken by mouth.[1]
It is on the World Health Organization's List of Essential Medicines.[2]
Adverse effects and safety
Side effects are those of the underlying medications.[1] Common side effects include poor coordination, poor appetite, nausea, numbness, and feeling tired. More severe side effects include liver problems.[3] Use is generally not recommended in children.[1] It is unclear if use is safe in pregnancy.[4]
Notes and References
- Book: WHO Model Formulary 2008 . 2009 . 9789241547659 . ((World Health Organization)) . Stuart MC, Kouimtzi M, Hill SR . 10665/44053 . World Health Organization . World Health Organization . free . 142 .
- Book: ((World Health Organization)) . World Health Organization model list of essential medicines: 21st list 2019 . 2019 . 10665/325771 . World Health Organization . World Health Organization . Geneva . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO . free .
- Web site: Isoniazid/rifampin Side Effects in Detail - Drugs.com. www.drugs.com. 18 December 2016. live. https://web.archive.org/web/20161221013120/https://www.drugs.com/sfx/isoniazid-rifampin-side-effects.html. 21 December 2016.
- Web site: Isoniazid / rifampin Use During Pregnancy Drugs.com. www.drugs.com. 18 December 2016. live. https://web.archive.org/web/20161221013132/https://www.drugs.com/pregnancy/isoniazid-rifampin.html. 21 December 2016.
