Isobutyryl chloride (2-methylpropanoyl chloride) is the organic compound with the formula . A colorless liquid, it the simplest branched-chain acyl chloride. It is prepared by chlorination of isobutyric acid.[1]
As an ordinary acid chloride, isobutyryl chloride is the subject of many reported transformations. Dehydrohalogenation of isobutyryl chloride with triethylamine gives 2,2,4,4-tetramethylcyclobutanedione. Treatment of isobutyryl chloride with hydrogen fluoride gives the acid fluoride.[2]