Isobutylamine Explained

Isobutylamine is an organic chemical compound (specifically, an amine) with the formula (CH₃)₂CHCH₂NH₂, and occurs as a colorless liquid.^{[1] [2]} Isobutylamine is one of the four isomeric amines of butane, the others being n-butylamine, sec-butylamine and tert-butylamine. It is the decarboxylated form of the amino acid valine, and the product of the metabolism thereof by the enzyme valine decarboxylase.

Isobutylamine is an odorant binding to TAAR3 in mice and can trigger sexual behaviour in male mice dependent on the cluster of TAAR2 through TAAR9.^[3]

Notes and References

1. http://www.chemicalbook.com/ChemicalProductProperty_EN_CB9211238.htm Isobutylamine
2. http://www.chemblink.com/products/78-81-9.htm Isobutylamine
3. Harmeier A, Meyer CA, Staempfli A, Casagrande F, Petrinovic MM, Zhang YP, Künnecke B, Iglesias A, Höner OP, Hoener MC . How Female Mice Attract Males: A Urinary Volatile Amine Activates a Trace Amine-Associated Receptor That Induces Male Sexual Interest . Frontiers in Pharmacology . 9 . 924 . 2018 . 30158871 . 6104183 . 10.3389/fphar.2018.00924 . free .