| Isle of the Senecas | |
| Map: | New York |
| Location: | Mohawk River |
| Coordinates: | 42.8206°N -73.9642°W[1] |
| Elevation Ft: | 217 |
| Country Admin Divisions Title: | State |
| Country Admin Divisions Title 1: | County |
| Country Admin Divisions 1: | Schenectady |
| Country Admin Divisions Title 2: | Towns |
| Country Admin Divisions 2: | Glenville |
Isle of the Senecas, also called Little Island, is an island in the Mohawk River south of Scotia in Schenectady County, New York.