| Isle-sur-Marne | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason Isle-sur-Marne.svg |
| Arrondissement: | Vitry-le-François |
| Canton: | Sermaize-les-Bains |
| Insee: | 51300 |
| Postal Code: | 51290 |
| Mayor: | Philippe Landroit[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Perthois-Bocage et Der |
| Coordinates: | 48.6414°N 4.6892°W |
| Elevation M: | 116 |
| Area Km2: | 5.47 |
Isle-sur-Marne (in French pronounced as /il syʁ maʁn/, literally Isle on Marne) is a commune in the Marne department in north-eastern France.