| Isla Piojo | |
| Image Caption: | Isla Piojo |
| Map: | Mexico |
| Location: | Gulf of California |
| Coordinates: | 29.0179°N -113.4652°W |
| Elevation M: | 65 |
| Country: | Mexico |
| Country Admin Divisions Title: | State |
| Country Admin Divisions: | Baja California |
| Population: | uninhabited |
Isla Piojo, or Lice Island, is an island in the Gulf of California, located within Bahía de los Ángeles east of the Baja California Peninsula. The island is uninhabited and is part of the Ensenada Municipality.
Isla Piojo has four species of reptiles: Crotalus mitchellii (speckled rattlesnake), Phyllodactylus nocticolus (peninsular leaf-toed gecko), Sauromalus hispidus (spiny chuckwalla), and Uta stansburiana (common side-blotched lizard).