| Isla Cayo | |
| Map: | Mexico |
| Location: | Gulf of California |
| Coordinates: | 24.8751°N -110.6036°W |
| Elevation M: | 20 |
| Country: | Mexico |
| Country Admin Divisions Title: | State |
| Country Admin Divisions: | Baja California Sur |
| Population: | Uninhabited |
Isla Cayo, is an island in the Gulf of California east of the Baja California Peninsula. The island is uninhabited and is part of the La Paz Municipality.
Isla Cayo has two species of reptiles: Phyllodactylus nocticolus (peninsular leaf-toed gecko), and Urosaurus nigricauda (black-tailed brush lizard).[1]