| Isili | |
| Official Name: | Comune di Isili |
| Native Name: | Ìsili |
| Pushpin Map: | Italy Sardinia |
| Coordinates: | 39.75°N 16°W |
| Region: | Sardinia |
| Mayor: | Orlando Carcangiu |
| Area Total Km2: | 68.0 |
| Population Footnotes: | [1] |
| Population Total: | 2950 |
| Population As Of: | 31 December 2010 |
| Population Demonym: | Isilesi |
| Elevation M: | 523 |
| Postal Code: | 08033 |
| Area Code: | 0782 |
Isili, Ìsili in sardinian language, is a comune (municipality) in the province of South Sardinia, southern Sardinia, Italy, located about 60km (40miles) north of Cagliari in the Sarcidano traditional region.
Isili borders the following municipalities: Gergei, Gesturi, Laconi, Nuragus, Nurallao, Nurri, Serri, Villanova Tulo.