Isay reaction explained

The Isay reaction also known as Gabriel-Isay condensation is an organic reaction in which certain diaminopyrimidines are transformed into pterins by condensation with a 1,2-dicarbonyl compound, such as 2,3-butanedione.^{[1] [2]} The reaction is named after Oskar Isay.

See also

• List of organic reactions

Notes and References

1. Oskar . Isay . Eine Synthese des Purins . . 1906 . 39 . 250 - 265 . 10.1002/cber.19060390149. .
2. 3925 - 3927 . 10.1021/jo00824a016 . Preparation of 6-substituted pterins via the Isay reaction . 1971 . Kaufman . Seymour . Storm . Carlyle B. . Shiman . Ross . . 36 . 25. .