| Isange | |
| Native Name: | Kata ya Isange |
| Native Name Lang: | sw |
| Settlement Type: | Ward |
| Pushpin Map: | Tanzania#Africa |
| Pushpin Relief: | yes |
| Coordinates: | -9.1667°N 83°W |
| Subdivision Type: | Country |
| Subdivision Type1: | Region |
| Subdivision Name1: | Mbeya Region |
| Subdivision Type2: | District |
| Subdivision Name2: | Busokelo District |
| Subdivision Type3: | Ward |
| Subdivision Name3: | Isange |
| Population As Of: | 2022 census |
| Population Total: | 5,587 |
| Postal Code: | 53531 |
| Postal Code Type: | Postcode |
| Timezone: | EAT |
| Utc Offset: | +3 |
Isange is an administrative ward in the Busokelo District of the Mbeya Region of Tanzania. In 2016 the Tanzania National Bureau of Statistics report there were 6,381 people in the ward, from 5,790 in 2012. Isange Health Center is located in the ward and serves its population. Dr. Peter Yusti is the medical officer in charge.
The ward has 4 villages and 22 vitongoji.