| Official Name: | Isakovo |
| Native Name: | Исаково |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Gryazovetsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 58.9167°N 80°W[1] |
Isakovo (Russian: Исаково) is a rural locality (a village) in Yurovskoye Rural Settlement, Gryazovetsky District, Vologda Oblast, Russia. The population was 9 as of 2002.[2] One of the earliest appearance of pottery has been found in Isakovo, alongside flint and bone tools (arrowheads, knives, points, half-ground adzes). Pointed-based pots in Isakovo probably were copies of similarly shaped baskets. The period of the artifacts and pottery may reach back to about 4000 BC.[3]
Isakovo is located 43 km northwest of Gryazovets (the district's administrative centre) by road. Zakharovo is the nearest rural locality.[4]