| Isador M. Sheffer | |
| Birth Date: | 15 October 1901 |
| Birth Place: | Massachusetts |
| Nationality: | American |
| Fields: | mathematics |
| Doctoral Advisor: | G. D. Birkhoff |
| Known For: | Sheffer sequence |
Isador Mitchell Sheffer (October 15, 1901 - April 20, 1992) was an American mathematician best known for the Sheffer sequence of polynomials.[1] Born in Massachusetts, he lived a large portion of his life in State College, Pennsylvania, where he was a Professor of Mathematics at Pennsylvania State University.
He received his PhD from Harvard University in 1927, under the direction of George Birkhoff.