| Isack Kamwelwe Aloyce | |
| Office: | Minister of Works, Transport and Communication |
| Term Start: | 1 July 2018 |
| Term End: | 16 June 2020 |
| President: | John Magufuli |
| Predecessor: | Makame Mbarawa |
| Successor: | Leonard Chamuriho |
| Order1: | 9th |
| Office1: | Minister of Water and Irrigation |
| Term Start1: | 7 October 2017 |
| Term End1: | 1 July 2018 |
| President1: | John Magufuli |
| Predecessor1: | Gerson Lwenge |
| Successor1: | Makame Mbarawa |
| Office2: | Member of Parliament for Katavi |
| Term End2: | 16 June 2020 |
| Term Start2: | 2015 |
| President2: | John Magufuli |
| Party: | CCM |
| Birth Date: | April 30, 1956 |
| Nationality: | Tanzanian |
Isack Aloyce Kamwelwe (born April 30, 1956) is a Tanzanian politician and a member of the Chama Cha Mapinduzi political party.[1] He was elected MP representing Katavi in 2015. He is also the Minister of Transport in Tanzania.[2] [3]