| Official Name: | Isabella Indian Reservation |
| Settlement Type: | Indian reservation |
| Image Map1: | 1610R Isabella Reservation Locator Map.svg |
| Map Caption1: | Location within the state of Michigan |
| Coordinates: | 43.6733°N -84.7761°W |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Michigan |
| Subdivision Type2: | Counties |
| Subdivision Name2: | Arenac |
| Government Footnotes: | [1] |
| Government Type: | Tribal Council |
| Leader Title: | Tribal Chief |
| Leader Name: | Theresa Jackson |
| Leader Title1: | Tribal Sub-Chief |
| Leader Name1: | Joseph Kequom |
| Area Footnotes: | [2] |
| Area Total Sq Mi: | 217.67 |
| Elevation Ft: | 745 |
| Population As Of: | 2010 |
| Population Footnotes: | [3] |
| Population Total: | 26,274 |
| Population Density Sq Mi: | auto |
| Timezone: | EST |
| Utc Offset: | -5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | -4 |
| Area Code: | 989 |
| Blank Name: | GNIS feature ID |
The Isabella Indian Reservation is the primary land base of the federally recognized Saginaw Chippewa Tribal Nation, located in Isabella County in the central part of the U.S. state of Michigan. The tribe also has some small parcels of off-reservation trust land in Standish Township, Arenac County, near Saginaw Bay and southeast of the city of Standish. Tribal lands are held in trust by the federal government on behalf of the nation. The tribe owns and operates the Soaring Eagle Casino & Resort in Mount Pleasant and the Saganing Eagles Landing Casino in Standish.
The Tribe entered into an agreement with the state to expand its law enforcement jurisdiction to enforce laws on its members. This expanded area is for law enforcement and its members only and not the Mt. Pleasant community as a whole.
All townships are in Isabella County, except Standish Township, which is in Arenac County