| Isabella Grimaldi | |
| Lady consort of Monaco | |
| Birth Date: | 15??2 |
| Death Date: | 1583 |
| House: | Grimaldi |
| Spouse: | Honoré I, Lord of Monaco |
| Issue: | Charles II, Lord of Monaco François of Monaco Horace of Monaco Hercules, Lord of Monaco |
| Father: | Giovanni Battista Grimaldi, Lord of Montaudion |
| Mother: | Maddalena Pallavicini |
Isabella Grimaldi (15?? – 1583), was Lady of Monaco by marriage to Honoré I, Lord of Monaco.[1]
Isabella was the daughter of Giovanni Battista Grimaldi, Lord of Montaudion, and Maddalena Pallavicini. She was the niece of Etienne (Stephen) Grimaldi (d. 1561), who was the regent of Honoré I during his minority (1532-1540) and continued to be the de facto ruler of Monaco until his death, and the marriage between Isabella and Honoré I was arranged by Etienne. The marriage took place in 1545. She was widowed in 1581.