| Isabela River | |
| Pushpin Map: | Dominican Republic |
| Pushpin Map Caption: | Location of mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | Dominican Republic |
The Isabela River is a river of the Dominican Republic.
This rises in Loma Siete Cabezas in the Sierra de Yamasá, inland of the island and empties into the Caribbean Sea, crossing through the port of Santo Domingo.
