| Isaac Garza Garza | |
| Birth Date: | 3 June 1853 |
| Birth Place: | Monterrey, Mexico |
| Death Place: | Monterrey, Mexico |
| Occupation: | Businessman |
| Spouse: | Consuelo Sada Muguerza |
| Children: | Rosario Garza Sada, Isaac Garza Sada, Roberto Garza Sada, Eugenio Garza Sada, Consuelo Garza Sada, Carmen Garza Sada, Angelina Garza Sada, Amparo Garza Sada |
Isaac Garza Garza (June 3, 1853 – May 1, 1933) was a Mexican businessman who redirected to industry the interests of the Garza family which, according to Fortune Magazine, are the Mexican equivalent of the Rockefellers.