| Isa bin Mohammed al Khalifa | |
| Native Name: | عيسى بن محمد آل خليفة |
| Native Name Lang: | ar |
| Birth Date: | November 25, 1938 |
| Birth Place: | Muharraq, Bahrain |
| Alma Mater: | Cairo University |
| Occupation: | civil servant |
| Children: | 3 |
| Relatives: | Hamad bin Isa Al Khalifa (nephew) |
| Family: | House of Al Khalifa |
Isa bin Muhammad Al Khalifa (Arabic: عيسى بن محمد آل خليفة; November 25, 1938, in Muharraq – August 13, 2015) was a Bahraini lawyer, judge, and minister. An uncle of King Hamad bin Isa Al Khalifa, Isa bin Muhammad directed the Al-Menber Islamic Society, the Bahraini branch of the Muslim Brotherhood, from 1963 until his death.
Born in Muharraq, Al Khalifa graduated from Al-Hidaya Al-Khalifia Boys School in 1950, then obtained his high school diploma from Helwan Technical Vocational Secondary School in 1956. He earned a Bachelor of Arts in Law from Cairo University in 1962.[1]
He was Minister of Justice and Islamic Affairs from 1974 to 1975, and Minister of Labor from 1975 to 1980.
Al Khalifa died after returning from medical treatment abroad on August 13, 2015, at the age of 77, and was buried on August 15, 2015, in Hunainiyah Cemetery in Riffa, Bahrain.[2]