| Isaías Guardiola | |
| Fullname: | Isaías Guardiola |
| Nationality: | Spanish |
| Birth Date: | 1 October 1984 |
| Birth Place: | Petrer, Spain |
| Height: | 2m (07feet) |
| Position: | Right back |
| Currentclub: | TBV Lemgo |
| Clubnumber: | 7 |
| Years1: | 2003–2005 |
| Clubs1: | Valencia |
| Years2: | 2005–2010 |
| Clubs2: | Ciudad Logroño |
| Years3: | 2010–2011 |
| Clubs3: | Ciudad Real |
| Years4: | 2011–2012 |
| Clubs4: | Atlético Madrid |
| Years5: | 2012–2014 |
| Clubs5: | Rhein-Neckar Löwen |
| Years6: | 2014–2015 |
| Clubs6: | Aalborg Håndbold |
| Years7: | 2015–2016 |
| Clubs7: | Pays d'Aix UC |
| Years8: | loan |
| Years9: | 2016–2018 |
| Clubs9: | HC Erlangen |
| Years10: | 2018–2023 |
| Clubs10: | TBV Lemgo |
| Nationalteam1: | Spain |
| Ntupdate: | 2012 |
Isaías Guardiola Villaplana (born 1 October 1984, in Petrer)[1] is a Spanish handballer who plays for TBV Lemgo and the Spanish national team. He is a twin brother of Gedeón Guardiola, also a handballer.