| Isômes | |
| Commune Status: | Commune |
| Arrondissement: | Langres |
| Canton: | Villegusien-le-Lac |
| Insee: | 52249 |
| Postal Code: | 52190 |
| Mayor: | Nicolas Hérard[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Auberive Vingeanne et Montsaugeonnais |
| Coordinates: | 47.6469°N 5.305°W |
| Elevation M: | 262 |
| Elevation Min M: | 256 |
| Elevation Max M: | 321 |
| Area Km2: | 10.63 |
| Demonym: | Isômois, Isômoises |
Isômes (in French pronounced as /isom/) is a commune in the Haute-Marne department in north-eastern France.