| Honorific-Prefix: | Prof. Dr. H. |
| Irwan Prayitno | |
| Honorific-Suffix: | M.Sc. |
| Office: | 9th Governor of West Sumatra |
| Term Start: | 12 February 2016 |
| Term End: | 12 February 2021 |
| President: | Joko Widodo |
| Predecessor: | Reydonnyzar Moenek (Acting) |
| Vicegovernor: | Nasrul Abit |
| Successor: | Alwis (daily caretaker) Hamdani (Acting) Mahyeldi Ansharullah |
| Term Start2: | 15 August 2010 |
| Term End2: | 15 August 2015 |
| President2: | Susilo Bambang Yudhoyono Joko Widodo |
| Predecessor2: | Marlis Rahman |
| Vicegovernor2: | Muslim Kasim |
| Successor2: | Reydonnyzar Moenek (Acting) |
| Birth Date: | 20 December 1963 |
| Birth Place: | Yogyakarta, Indonesia |
| Children: | Jundy Fadhlillah Wafiatul Ahdi Dhiya'u Syahidah Anwar Jundy Atika Ibrahim Shohwatul Ishlah Farhana Irwan Laili Tanzila |
| Profession: | Politician, writers |
| Party: | Prosperous Justice Party |
| Alma Mater: | University of Indonesia Universiti Putra Malaysia |
| Website: | irwan-prayitno.com |
Irwan Prayitno (born 20 December 1963) is an Indonesian politician who was serving as the governor of West Sumatra province. He was elected in the 2010 and 2015 election for the five-year period 2010–2015 and 2016–2021. Before his election as governor, he served as a member of Indonesia's Parliament (DPR-RI) from the election region of West Sumatra for three consecutive periods (1999–2004, 2004–2009, and 2009–2014).
With 32,44% votes, Irwan Prayitno is the second governor of West Sumatra elected by direct popular vote. He was sworn into office along with his deputy governor, Muslim Kasim by the Minister of Home Affairs Gamawan Fauzi on 15 August 2010.
Irwan Prayitno was born in Yogyakarta, Indonesia. His father, Djamrul Djamal, was from Padang, and his mother, Sudarni Sayuti, was from Tanah Datar, West Sumatra. After graduating his secondary school at SMA Negeri 3 (Public Senior High School 3) in Padang, Prayitno pursued his studies at the Faculty of Psychology University of Indonesia from 1982 to 1988. Prayitno continued his education at Putra University in Malaysia where he obtained his master and PhD.
In the 2009 legislative election, Prayitno was elected as a member of the People's Representative Council (DPR-RI) from the Partai Keadilan Sejahtera (Prosperous Justice Party). Prayitno resigned from the DPR-RI because he decided to run for the election as governor of West Sumatra on 30 June 2010.