| Competition: | Irish League Premier Division |
| Season: | 2000–01 |
| Winners: | Linfield 44th Irish title |
| Relegated: | Ballymena United |
| Matches: | 180 |
| Total Goals: | 507 |
| League Topscorer: | Davy Larmour (17) |
| Prevseason: | 1999–2000 |
| Nextseason: | 2001–02 |
The 2000–01 Irish League was the 100th edition of the Irish League, the highest level of league competition in Northern Irish football. The league consisted of 10 teams, and Linfield won the championship.
| Competition: | Irish League First Division |
| Winners: | Ards |
| Promoted: | Ards |
| Matches: | 180 |
| Total Goals: | 527 |
| Prevseason: | 1999–00 |
| Nextseason: | 2001–02 |
Crusaders, who finished in the relegation play-off place, faced Lisburn Distillery, the 2nd-placed team in the First Division, in a two-legged tie for a place in next season's Irish League Premier Division.
----Crusaders won 4–3 on aggregate