| Subdivision Type: | Country |
| Timezone: | CET |
| Utc Offset: | +1 |
| Timezone Dst: | CEST |
| Utc Offset Dst: | +2 |
| Official Name: | Iregszemcse |
| Subdivision Type1: | County |
| Subdivision Name1: | Tolna |
| Area Total Km2: | 58.33 |
| Population Total: | 2600[1] |
| Population As Of: | 2017 |
| Population Density Km2: | auto |
| Postal Code Type: | Postal code |
| Postal Code: | 7095 |
| Area Code: | 74 |
| Pushpin Map: | Hungary |
| Pushpin Map Caption: | Location of Iregszemcse |
| Coordinates: | 46.6977°N 18.1806°W |
| Leader Title: | Mayor |
| Leader Name: | Tóth Szabolcs |
Iregszemcse, also called Ireg-Szemcse, is a village in Tolna County, Hungary.
Iregszemcse was first mentioned articles of IV. Béla's abbey where it was a royal estate until 1387. Following a period where Hungary was controlled by the Ottoman Empire, it was resettled by Hungary nobleman Ádám Viczay in the 1600s.[2]
The two villages Felső-Ireg and Szemcséd were joined in 1938.
On 15 January 2023, a mayoral election was held and saw Independent candidate Tóth Szabolcs win 434 votes (42.14%) out of five other independent candidates.[3]