| Ipixuna River | |
| Pushpin Map: | Brazil |
| River System: | Purus River |
| Mouth Location: | Tapauá, Amazonas |
| Mouth Coordinates: | -5.626°N -63.1927°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
The Ipixuna River (Portuguese: Rio Ipixuna) or Paranápixuna River[1] is a river of Amazonas state in north-western Brazil.It is a tributary of the Purus River. The confluence of these two rivers is at Tapauá.
The Ipixuna River flows from south to north through the Tapauá State Forest, created in 2009, before joining the Purus river from the right at Tapauá.The river flows through the Purus-Madeira moist forests ecoregion in its upper reaches.It flows through the Purus várzea ecoregion before joining the Purus.