Iodophenpropit Explained

Iodophenpropit is a histamine antagonist which binds selectively to the H3 subtype. Its 125I radiolabelled form has been used for mapping the distribution of H3 receptors in animal studies.[1] [2]

References

  1. Jansen . FP . Wu . TS . Voss . HP . Steinbusch . HW . Vollinga . RC . Rademaker . B . Bast . A . Timmerman . H . Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, 125I-iodophenpropit, to rat brain . . 113 . 2 . 355–62 . 1994 . 7834183 . 1510107 . 10.1111/j.1476-5381.1994.tb16995.x.
  2. Jansen . FP . Mochizuki . T . Maeyama . K . Leurs . R . Timmerman . H . Characterization of histamine H3 receptors in mouse brain using the H3 antagonist 125Iiodophenpropit . Naunyn-Schmiedeberg's Archives of Pharmacology . 362 . 1 . 60–7 . 2000 . 10935534 . 10.1007/s002100000227 . 21293180 .

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