| Tourney Name: | InterLiga |
| Year: | 2006 |
| Other Titles: | InterLiga |
| Size: | 200px |
| Country: | USA |
| Dates: | 5 January 2006 - 15 January 2006 |
| Num Teams: | 8 |
| Confederations: | the FMF |
| Venues: | 4 |
| Cities: | 4 |
| Matches: | 14 |
| Champion Other: | UANL |
| Count: | 2 |
| Second Other: | Guadalajara |
| Prevseason: | 2005 |
| Nextseason: | 2007 |
America was originally set to participate in the 2006 InterLiga tournament, but their 2005 clausura championship qualified the team for the 2006 CONCACAF Champions' Cup. Therefore, the club was replaced by Cruz Azul. The teams Tigres and Chivas de Guadalajara qualified to Copa Libertadores 2006
Matches at Reliant Stadium (Houston, Texas)
| 1. | 4 Jan 06 | Cruz Azul vs Necaxa | 0-1 | |
| 2. | 4 Jan 06 | UANL vs Guadalajara | 3-5 |
Matches at La Joya Stadium (La Joya, Texas)
| 3. | 5 Jan 06 | Pachuca vs Veracruz | 2-3 | |
| 4. | 5 Jan 06 | Monterrey vs Morelia | 2-2 |
Matches at Pizza Hut Park (Frisco, Texas)
| 5. | 7 Jan 06 | Necaxa vs UANL | 2-3 | |
| 6. | 7 Jan 06 | Guadalajara vs Cruz Azul | 2-2 | |
| 7. | 8 Jan 06 | Morelia vs Pachuca | 1-2 | |
| 8. | 8 Jan 06 | Veracruz vs Monterrey | 1-2 |
Matches at The Home Depot Center (Carson, California)
| 9. | 10 Jan 06 | Tigres vs Cruz Azul | 4-0 | |
| 10. | 10 Jan 06 | Necaxa vs Guadalajara | 1-1 | |
| 11. | 11 Jan 06 | Morelia vs Veracruz | 0-1 | |
| 12. | 11 Jan 06 | Monterrey vs Pachuca | 1-1 | |
| 13. | 15 Jan 06 | Final 1: UANL vs Monterrey | 2-1 aet | |
| 14. | 15 Jan 06 | Final 2: Veracruz vs Guadalajara | 1-2 |