QIAGEN Silicon Valley explained

QIAGEN Silicon Valley
Industry:Software
Founded:2003
Hq Location:Redwood City, California

QIAGEN Silicon Valley (formerly Ingenuity Systems) is a company based in Redwood City, California, USA, that develops software to analyze complex biological systems. QIAGEN Silicon Valley's first product, IPA, was introduced in 2003, and is used to help researchers analyze omics data and model biological systems. The software has been cited in thousands of scientific molecular biology publications and is one of several tools for systems biology researchers and bioinformaticians in drug discovery and institutional research.

Technology

All QIAGEN Silicon Valley products use the Ingenuity Knowledge Base, which contains biological and chemical interactions and functional annotations created from millions of individually modeled relationships between proteins, genes, complexes, cells, tissues, drugs, and diseases. Each relationship originates from reported experimental facts from primary literature sources, including peer-reviewed journal articles and textbooks. The knowledge acquisition and extraction process is protected by multiple US Patents.[1]

Products and services

IPA is used among in the life science community and has been cited in thousands of peer-reviewed journal articles.[2] IPA can be used with or without data. IPA helps researchers analyze data derived from expression and SNP microarrays, proteomics experiments, and small-scale experiments that generate gene lists, in order to gain insight into molecular and chemical interactions, cellular phenotypes, and disease processes within a system. IPA also lets researchers search for information on genes, proteins, chemicals, drugs, and reagents. Resulting information can be used to build biological models, design experiments, or get up to speed in an area of research.[3]

Ingenuity offers search and visualization tools for science related e-commerce websites. Ingenuity has two prominent partnerships: Sigma-Aldrich leverages Ingenuity technology in their Your Favorite Gene application, and BD Biosciences leverages Ingenuity technology in their BD Cell Pathways[4] application.

Timeline

2003 - Ingenuity first offers Ingenuity Knowledge Base[5]
2004 - Stanford University licenses IPA[6]
2004 - Independent analysis finds significant ROI for pharmaceutical companies using IPA[7]
2005 - US Food and Drug Administration adopts IPA to review pharmacogenomics submissions[8]
2006 - Ingenuity enters into partnerships with Asuragen, Spotfire, Agilent, Genedata, and Inforsense[9]
2007 - Ingenuity introduces toxicology and biomarker capabilities within IPA 5.0[10]
2007 - IPA 5.0 wins Best in Show - Best New Product at Bio-IT World[11]
2007 - Ingenuity and FDA enter three year collaboration to enhance regulatory review process[12]
2008 - IPA's newest feature, Path Designer, wins Best New Product at Molecular Medicine[13]
2009 - Sigma Aldrich launches Your Favorite Gene - Powered by Ingenuity[14]
2009 - BD Biosciences launches BD Cell Pathways, powered by Ingenuity[15]
2011 - Ingenuity announces early access to Ingenuity iReport[16]
2012 - Ingenuity announces commercial availability of Ingenuity iReport and Ingenuity Variant Analysis[17] [18]
2013 - Ingenuity announces collaborations with both Laboratory Corporation and Quest Diagnostics to develop a solution for scoring genetic variation for next generation sequencing data (NGS) and is purchased by QIAGEN in May of the same year

See also

External links

Notes and References

  1. Web site: United States Patent: 7943742 . US Patent Office . April 7, 2012.
  2. Web site: Bibliography . Ingenuity Systems . April 7, 2012.
  3. Web site: Ingenuity IPA Software - Pathway Analysis, miRNA, NGS, RNA-Seq, Microarrays, Gene Expression, Biomarkers . Ingenuity Systems . April 7, 2012.
  4. http://www.bdbiosciences.com/pathways/index.jsp BD Cell Pathways
  5. Ingenuity Systems Announces Immediate Availability Of The Ingenuity Pathways Knowledge Base . Ingenuity Systems . May 27, 2003 . April 7, 2012.
  6. Stanford University Licenses IPA, Collaborates on Systems Biology Solutions . Ingenuity Systems . November 3, 2003 . April 7, 2012.
  7. "The Return on Investment for Ingenuity Pathways Analysis within the Pharmaceutical Value Chain", Zimmerman, Reeve, and Golden, Life Science Insights, an IDC company, July 2004
  8. The U.S. Food and Drug Administration to use IPA in review of Pharmacogenomics Submissions . Ingenuity Systems . June 21, 2005 . April 7, 2012.
  9. Web site: Press release archive . Ingenuity Systems . April 7, 2012.
  10. Ingenuity Systems releases IPA™ 5.0 software, offering new biomarker and molecular toxicology capabilities . Ingenuity Systems . April 17, 2007 . April 7, 2012.
  11. News: Best of Show: Life Science Software & Informatics . Bio-IT World . June 13, 2007 . April 7, 2012.
  12. Ingenuity Systems and FDA Enter 3-Year, $6 Million Collaboration to Enhance Regulatory Review Process . Ingenuity Systems . November 27, 2007 . April 7, 2012.
  13. Best of Show Award Winners Named at the Fifteenth International Molecular Medicine Tri-Conference . Cambridge Healthtech Institute . April 3, 2008 . April 7, 2012.
  14. Sigma-Aldrich Launches Your Favorite Gene Powered by Ingenuity, Sigma-Aldrich Co . Sigma-Aldrich Co., Inc. . January 27, 2009 . April 7, 2012.
  15. Ingenuity's Technology Powers BD Cell Pathways Tool on New BD Biosciences Website . Ingenuity Systems . August 10, 2009 . April 7, 2012.
  16. Ingenuity Systems Unveils Early Access to Revolutionary New iReport . https://web.archive.org/web/20160305090803/http://www.prweb.com/releases/2011/9/prweb8829357.htm . dead . March 5, 2016 . Ingenuity Systems . September 29, 2011 . April 7, 2012.
  17. News: New Products: Randox Laboratories' Beta-Lactams Array; Ingenuity Systems' iReport . BioArray News . GenomeWeb . January 24, 2012 . April 7, 2012.
  18. News: Ingenuity Preps New NGS Variant Analysis Tool, Signs Translational Oncology Group as Beta Tester . BioInform . GenomeWeb . January 13, 2012 . April 7, 2012.