thumb|right|Infulene River imaged by Sentinel-2The Infulene River (pt|Rio Infulene) is a small river about 20 km long, running from north to south, in the Mozambican province Maputo, flowing into the Estuário do Espírito Santo,[1] serving as a boundary between the municipalities of Maputo and Matola.
It is widely used for irrigating horticultural products in the so-called Green Zones of Maputo City, leading to a considerable increase in salinity and pollution of its waters.[2]