Inflammatory pseudotumor explained

An inflammatory pseudotumor is a cell proliferation and inflammation involving spindle cells, which may occur in many parts of the body, and is of unknown case.^[1]

According to the WHO classification, three lesional patterns can be observed:

• Inflammatory myofibroblastic tumour, that can be associated with an ALK gene rearrangement
• Plasmocytic pattern ("plasma cell granuloma"), that can be linked to IgG4-related disease
• Fibrous and hyalinizing pattern: Pulmonary hyalinizing granuloma

Notes and References

1. Book: Gnepp . Douglas R. . Bishop . Justin A. . Gnepp's Diagnostic Surgical Pathology of the Head and Neck . 5 May 2020 . Elsevier Health Sciences . 978-0-323-54780-2 . 984 . en.