| State: | IN |
| Type: | IN |
| Route: | 48 |
| Map Custom: | yes |
| Map Notes: | SR 48 highlighted in red |
| Length Mi: | 62.426 |
| Section1: | Western segment |
| Length Mi1: | 29.963 |
| Established: | October 1, 1926[1] |
| Direction A1: | West |
| Terminus A1: | in Fairbanks |
| Junction1: | in Shelburn in North Liberty |
| Direction B1: | East |
| Terminus B1: | in Worthington |
| Section2: | Central segment |
| Length Mi2: | 5.991 |
| Direction A2: | West |
| Terminus A2: | in Whitehall |
| Direction B2: | East |
| Terminus B2: | in Bloomington |
| Section3: | Eastern segment |
| Length Mi3: | 26.472 |
| Direction A3: | West |
| Terminus A3: | in Napoleon |
| Direction B3: | East |
| Terminus B3: | in Lawrenceburg |
| Counties: | Clay, Dearborn, Greene, Monroe, Owen, Ripley, Sullivan |
| Previous Type: | IN |
| Previous Route: | 47 |
| Next Type: | IN |
| Next Route: | 49 |
State Road 48 (SR 48) in the U.S. State of Indiana is an east - west state highway running through southern Indiana. It has three distinct and separate sections. The western terminus of SR 48 is at State Road 63 and the eastern terminus at U.S. Route 50.
The western section begins at SR 63 and heads east towards Jasonville. Passing through Shelburn at an intersection with U.S. Route 41 (US 41) and U.S. Route 150 (US 150). East of Jasonville SR 48 heads east towards Worthington. Northwest of Worthington SR 48 ends at State Road 157.
The middle section of SR 48 begins at an intersection with State Road 43 and SR 48 heads east towards Bloomington. The eastern terminus of this section is at an interchange with Interstate 69 and State Road 45 (SR 45) in Bloomington.
The eastern section begins at an intersection with State Road 229 and SR 48 heads east from that intersection. SR 48 passes through intersection with State Road 129, State Road 101, and State Road 148 before entering Lawrenceburg. In Lawrenceburg SR 48 has an intersection with US 50, this intersection is the eastern terminus of SR 48.