| Independent Socialist Republican Party | |
| Colorcode: | Red |
| Leader: | Blaise Diagne |
| Foundation: | 1919 |
| Country: | Senegal |
| Position: | Left-wing |
Independent Socialist Republican Party (in French: Parti Républicain Socialiste Indépendant) was a political party in Senegal, formed in 1919 by Blaise Diagne.
In the December 21, 28 1919 municipal elections the multiracial lists of PRSI won in all four municipalities.