IgSF CAM explained

IgSF CAMs (Immunoglobulin-like Cell Adhesion Molecules) are cell adhesion molecules that belong to Immunoglobulin superfamily.[1] It is regarded as the most diverse superfamily of CAMs. This family is characterized by their extracellular domains containing Ig-like domains. The Ig domains are then followed by Fibronectin type III domain repeats and IgSFs are anchored to the membrane by a GPI moiety. This family is involved in both homophilic or heterophilic binding and has the ability to bind integrins or different IgSF CAMs.

Examples

Here is a list of some molecules of this family:

Notes and References

  1. Book: Lajtha A, Banik NL, Banik N . Handbook of neurochemistry and molecular neurobiology: Neural protein metabolism and function. 28 November 2010. 2007. シュプリンガー・ジャパン株式会社. 978-0-387-30346-8. 41–.