Imidazolone Explained

Imidazolinones or imidazolones are a family of heterocyclic compounds, the parents of which have the formula OC(NH)2(CH)2. Two isomers are possible, depending on the location of the carbonyl (CO) group. The NH groups are nonadjacent. A common route to imidazol-2-ones involves condensation of ureas and acyloins.[1] Some are of interest in the pharmaceuticals.[2] 4-Imidazolones arise from the condensation of amidines with 1,2-dicarbonyls such as glyoxal.

References

  1. Org. Synth.. 1932. 12. 34. 10.15227/orgsyn.012.0034. 4,5-Diphenylglyoxalone. B. B.. Corson. Emeline. Freeborn.
  2. Chemistry of Heterocyclic Compounds. 2015. 51. 395–420 . Methods for the synthesis of 1-substituted 1H-imidazol-2(3H)-ones. Maria M.. Antonova. Vladimir V.. Baranov. Angelina N.. Kravchenko. 10.1007/s10593-015-1716-3.