| Ilișoara Mare | |
| Pushpin Map: | Romania |
| Subdivision Type1: | Country |
| Subdivision Name1: | Romania |
| Subdivision Type2: | Counties |
| Subdivision Name2: | Mureș County |
| Length: | 14km (09miles) |
| Mouth: | Ilva |
| Mouth Coordinates: | 46.9952°N 25.1171°W |
| Progression: | Ilva→ |
| Basin Size: | 48km2 |
| Tributaries Left: | Cocoș |
| Tributaries Right: | Pârâul Rău, Ursul Mare, Ilișoara Mică |
The Ilișoara Mare is a left tributary of the river Ilva in Romania. It flows into the Ilva north of Lunca Bradului. Its length is 14km (09miles) and its basin size is 48km2.