| Type: | Cardinal |
| Honorific Prefix: | His Eminence |
| Ignazio Masotti | |
| Prefect of the Congregation of Bishops and Regulars | |
| Church: | Roman Catholic Church |
| Appointed: | 12 August 1886 |
| Term End: | 31 October 1888 |
| Predecessor: | Innocenzo Ferrieri |
| Successor: | Isidoro Verga |
| Other Post: | Cardinal-Deacon of San Cesareo in Palatio (1884-88) |
| Cardinal: | 10 November 1884 |
| Created Cardinal By: | Pope Leo XIII |
| Rank: | Cardinal-Deacon |
| Birth Name: | Ignazio Masotti |
| Birth Date: | 16 January 1817 |
| Birth Place: | Forlì, Papal States |
| Death Place: | Palazzo Altemps, Rome, Kingdom of Italy |
| Buried: | Campo Verano |
| Previous Post: | Secretary of the Congregation of Bishops and Regulars (1882-86) |
Ignazio Masotti (16 January 1817 – 31 October 1888) was an Italian cardinal.