IVNS1ABP explained

Influenza virus NS1A-binding protein is a protein that in humans is encoded by the IVNS1ABP gene.^{[1] [2] [3]}

In melanocytic cells IVNS1ABP gene expression may be regulated by MITF.^[4]

Further reading

• Perconti G, Ferro A, Amato F, etal . The kelch protein NS1-BP interacts with alpha-enolase/MBP-1 and is involved in c-Myc gene transcriptional control. . Biochim. Biophys. Acta . 1773 . 12 . 1774–85 . 2008 . 17996313 . 10.1016/j.bbamcr.2007.09.002 .
• Dunham EE, Stevens EA, Glover E, Bradfield CA . The aryl hydrocarbon receptor signaling pathway is modified through interactions with a Kelch protein. . Mol. Pharmacol. . 70 . 1 . 8–15 . 2006 . 16582008 . 10.1124/mol.106.024380 . 8164208 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Zhang QH, Ye M, Wu XY, etal . Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. . Genome Res. . 10 . 10 . 1546–60 . 2001 . 11042152 . 10.1101/gr.140200 . 310934 .
• Harris CE, Boden RA, Astell CR . A novel heterogeneous nuclear ribonucleoprotein-like protein interacts with NS1 of the minute virus of mice. . J. Virol. . 73 . 1 . 72–80 . 1999 . 9847309 . 10.1128/JVI.73.1.72-80.1999. 103810 .

Notes and References

1. Wolff T, O'Neill RE, Palese P . NS1-Binding protein (NS1-BP): a novel human protein that interacts with the influenza A virus nonstructural NS1 protein is relocalized in the nuclei of infected cells . J Virol . 72 . 9 . 7170–80 . Sep 1998 . 9696811 . 109939 . 10.1128/JVI.72.9.7170-7180.1998.
2. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O . Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro . DNA Res . 5 . 6 . 355–64 . May 1999 . 10048485 . 10.1093/dnares/5.6.355 . free .
3. Web site: Entrez Gene: IVNS1ABP influenza virus NS1A binding protein.
4. Hoek KS, Schlegel NC, Eichhoff OM, etal . Novel MITF targets identified using a two-step DNA microarray strategy . Pigment Cell Melanoma Res. . 21 . 6 . 665–76 . 2008 . 19067971 . 10.1111/j.1755-148X.2008.00505.x . 24698373 . free .