Interleukin-22 receptor explained

interleukin 22 receptor, alpha 1
Hgncid:13700
Symbol:IL22RA1
Altsymbols:IL22R
Entrezgene:58985
Omim:605457
Refseq:NM_021258
Uniprot:A8K839
Chromosome:1
Arm:p
Band:36.11
interleukin 22 receptor, alpha 2
Hgncid:14901
Symbol:IL22RA2
Entrezgene:116379
Omim:606648
Refseq:NM_181310
Uniprot:Q969J5
Chromosome:6
Arm:q
Band:24.1
Locussupplementarydata:-24.2

Interleukin-22 receptor is a type II cytokine receptor. It binds to Interleukin-22. It is a heterodimer of α1[1] and IL-10Rβ2 subunits.

Notes and References

  1. Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL . Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R . J. Biol. Chem. . 275 . 40 . 31335–9 . 2000 . 10875937 . 10.1074/jbc.M005304200 . free .