Interleukin-18 receptor explained

interleukin 18 receptor 1
Hgncid:	5988
Symbol:	IL18R1
Altsymbols:	IL1RRP, IL-1Rrp, CD218a
Entrezgene:	8809
Omim:	604494
Refseq:	NM_003855
Uniprot:	Q13478
Chromosome:	2
Arm:	q
Band:	12

interleukin 18 receptor accessory protein
Hgncid:	5989
Symbol:	IL18RAP
Altsymbols:	AcPL, CD218b
Entrezgene:	8807
Omim:	604509
Refseq:	NM_003853
Uniprot:	O95256
Chromosome:	2
Arm:	p
Band:	24.3-24.1

The interleukin-18 receptor (IL-18R) is an interleukin receptor of the immunoglobulin superfamily.^{[1] [2]}

Endometrial IL-18 receptor mRNA and the ratio of IL-18 binding protein to interleukin 18 are significantly increased in adenomyosis patients in comparison to normal people, indicating a role in its pathogenesis.^[3]

Notes and References

1. Sergi B, Penttila I . Interleukin 18 receptor . J. Biol. Regul. Homeost. Agents . 18 . 1 . 55–61 . 2004 . 15323361 .
2. Wu C, Sakorafas P, Miller R, McCarthy D, Scesney S, Dixon R, Ghayur T . IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction . J. Immunol. . 170 . 11 . 5571–7 . 2003 . 12759435 . 10.4049/jimmunol.170.11.5571. free .
3. 94. Fertility and Sterility. Eutopic endometrial interleukin-18 system mRNA and protein expression at the level of endometrial-myometrial interface in adenomyosis patients . Y.. 1. 33–39. 10.1016/j.fertnstert.2009.01.132. 19394601. 2010. Soong . H. . H.. Yu . H.. Chan . S.. Wang . C.. Lee. Huang. free.