IGHG3 explained

Ig gamma-3 chain C region is a protein that in humans is encoded by the IGHG3 gene.^{[1] [2]}

Further reading

• Michaelsen TE, Frangione B, Franklin EC . Primary structure of the "hinge" region of human IgG3. Probable quadruplication of a 15-amino acid residue basic unit. . J. Biol. Chem. . 252 . 3 . 883–9 . 1977 . 10.1016/S0021-9258(19)75181-3 . 402363 . free .
• Wolfenstein-Todel C, Frangione B, Prelli F, Franklin EC . The amino acid sequence of "heavy chain disease" protein ZUC. Structure of the Fc fragment of immunoglobulin G3. . Biochem. Biophys. Res. Commun. . 71 . 4 . 907–14 . 1976 . 823945 . 10.1016/0006-291X(76)90741-5 .
• Huck S, Fort P, Crawford DH, etal . Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human C gamma genes. . Nucleic Acids Res. . 14 . 4 . 1779–89 . 1986 . 3081877 . 10.1093/nar/14.4.1779 . 339572 .
• Frangione B, Rosenwasser E, Prelli F, Franklin EC . Primary structure of human gamma 3 immunoglobulin deletion mutant: gamma 3 heavy-chain disease protein Wis. . Biochemistry . 19 . 18 . 4304–8 . 1980 . 6774747 . 10.1021/bi00559a024 .
• Lewis AP, Lemon SM, Barber KA, etal . Rescue, expression, and analysis of a neutralizing human anti-hepatitis A virus monoclonal antibody. . J. Immunol. . 151 . 5 . 2829–38 . 1993 . 10.4049/jimmunol.151.5.2829 . 8395549 . 24962823 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Bouwmeester T, Bauch A, Ruffner H, etal . A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. . Nat. Cell Biol. . 6 . 2 . 97–105 . 2004 . 14743216 . 10.1038/ncb1086 . 11683986 .

Notes and References

1. Alexander A, Steinmetz M, Barritault D, Frangione B, Franklin EC, Hood L, Buxbaum JN . gamma Heavy chain disease in man: cDNA sequence supports partial gene deletion model . Proc Natl Acad Sci U S A . 79 . 10 . 3260–4 . Sep 1982 . 6808505 . 346395 . 10.1073/pnas.79.10.3260 . 1982PNAS...79.3260A . free .
2. Web site: Entrez Gene: IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker).