IFNA5 explained
Interferon alpha-5 is a protein that in humans is encoded by the IFNA5 gene.[1] [2]
Further reading
- Henco K, Brosius J, Fujisawa A, etal . Structural relationship of human interferon alpha genes and pseudogenes. . J. Mol. Biol. . 185 . 2 . 227–60 . 1985 . 4057246 . 10.1016/0022-2836(85)90401-2 .
- Goeddel DV, Leung DW, Dull TJ, etal . The structure of eight distinct cloned human leukocyte interferon cDNAs. . Nature . 290 . 5801 . 20–6 . 1981 . 6163083 . 10.1038/290020a0 . 1981Natur.290...20G . 1900300 .
- Tiefenbrun N, Melamed D, Levy N, etal . Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. . Mol. Cell. Biol. . 16 . 7 . 3934–44 . 1996 . 8668211 . 10.1128/MCB.16.7.3934. 231390 .
- Chuntharapai A, Gibbs V, Lu J, etal . Determination of residues involved in ligand binding and signal transmission in the human IFN-alpha receptor 2. . J. Immunol. . 163 . 2 . 766–73 . 1999 . 10.4049/jimmunol.163.2.766 . 10395669 .
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
- Humphray SJ, Oliver K, Hunt AR, etal . DNA sequence and analysis of human chromosome 9. . Nature . 429 . 6990 . 369–74 . 2004 . 15164053 . 10.1038/nature02465 . 2734081 . 2004Natur.429..369H .
- Zhang Z, Henzel WJ . Signal peptide prediction based on analysis of experimentally verified cleavage sites. . Protein Sci. . 13 . 10 . 2819–24 . 2005 . 15340161 . 10.1110/ps.04682504 . 2286551 .
- Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
Notes and References
- Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO . Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia . Genomics . 14 . 2 . 437–43 . Dec 1992 . 1385305 . 10.1016/S0888-7543(05)80238-1 .
- Web site: Entrez Gene: IFNA5 interferon, alpha 5.