IFNA4 explained

Interferon alpha-4 is a protein that in humans is encoded by the IFNA4 gene.^{[1] [2]}

Further reading

• Mizoguchi J, Pitha PM, Raj NB . Efficient expression in Escherichia coli of two species of human interferon-alpha and their hybrid molecules. . DNA . 4 . 3 . 221–32 . 1985 . 3891272 . 10.1089/dna.1985.4.221 .
• Henco K, Brosius J, Fujisawa A, etal . Structural relationship of human interferon alpha genes and pseudogenes. . J. Mol. Biol. . 185 . 2 . 227–60 . 1985 . 4057246 . 10.1016/0022-2836(85)90401-2 .
• Linnane AW, Beilharz MW, McMullen GL, etal . Nucleotide sequence and expression in E. coli of a human interferon-alpha gene selected from a genomic library using synthetic oligonucleotides. . Biochem. Int. . 8 . 5 . 725–32 . 1984 . 6089830 .
• Tiefenbrun N, Melamed D, Levy N, etal . Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest . Mol. Cell. Biol. . 16 . 7 . 3934–44 . 1996 . 8668211 . 10.1128/MCB.16.7.3934. 231390 .
• Hussain M, Gill DS, Liao MJ . Both variant forms of interferon-alpha4 gene (IFNA4a and IFNA4b) are present in the human population . J. Interferon Cytokine Res. . 17 . 9 . 559–66 . 1997 . 9335434 . 10.1089/jir.1997.17.559 .
• Nyman TA, Tölö H, Parkkinen J, Kalkkinen N . Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes . Biochem. J. . 329 . Pt 2. 295–302 . 1998 . 9425112 . 10.1042/bj3290295. 1219044 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Yokota S, Yokosawa N, Okabayashi T, etal . Induction of Suppressor of Cytokine Signaling-3 by Herpes Simplex Virus Type 1 Contributes to Inhibition of the Interferon Signaling Pathway . J. Virol. . 78 . 12 . 6282–6 . 2004 . 15163721 . 10.1128/JVI.78.12.6282-6286.2004 . 416529 .
• Humphray SJ, Oliver K, Hunt AR, etal . DNA sequence and analysis of human chromosome 9 . Nature . 429 . 6990 . 369–74 . 2004 . 15164053 . 10.1038/nature02465 . 2734081 . 2004Natur.429..369H .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .

Notes and References

1. Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO . Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia . Genomics . 14 . 2 . 437–43 . Dec 1992 . 1385305 . 10.1016/S0888-7543(05)80238-1 .
2. Web site: Entrez Gene: IFNA4 interferon, alpha 4.