IFNA13 explained

Interferon alpha-1/13, also known as IFN-alpha-1/13, is a protein that in humans is encoded by the IFNA1 and IFNA13 genes.^{[1] [2]}

Further reading

• Nyman TA, Tölö H, Parkkinen J, Kalkkinen N . Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes. . Biochem. J. . 329 . 2. 295–302 . 1998 . 9425112 . 10.1042/bj3290295. 1219044.
• Davila S . New genetic associations detected in a host response study to hepatitis B vaccine . Genes Immun. . 11 . 3 . 232–8 . 2010 . 20237496 . 10.1038/gene.2010.1 . Froeling FE . Tan A . Bonnard . C . Boland . G J . Snippe . H . Hibberd . M L . Seielstad . M . 11183658 .
• Weber H, Weissmann C . Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli . Nucleic Acids Res. . 11 . 16 . 5661–9 . 1983 . 6310510 . 10.1093/nar/11.16.5661. 326304.
• Lamesch P . hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes . Genomics . 89 . 3 . 307–15 . 2007 . 17207965 . 4647941 . 10.1016/j.ygeno.2006.11.012 . Li N . Milstein S . Fan . Changyu . Hao . Tong . Szabo . Gabor . Hu . Zhenjun . Venkatesan . Kavitha . Bethel . Graeme .
• Goeddel DV . The structure of eight distinct cloned human leukocyte interferon cDNAs . Nature . 290 . 5801 . 20–6 . 1981 . 6163083 . 10.1038/290020a0 . Leung DW . Dull TJ . Gross . Mitchell . Lawn . Richard M. . McCandliss . Russell . Seeburg . Peter H. . Ullrich . Axel . Yelverton . Elizabeth. 1981Natur.290...20G . 1900300 .
• Myers MP . TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B . J. Biol. Chem. . 276 . 51 . 47771–4 . 2001 . 11694501 . 10.1074/jbc.C100583200 . Andersen JN . Cheng A . Tremblay . ML . Horvath . CM . Parisien . JP . Salmeen . A . Barford . D . Tonks . NK . free.
• Hussain M, Ni D, Gill D, Liao MJ . IFN-alpha1a gene is the major variant in the North American population . J. Interferon Cytokine Res. . 20 . 9 . 763–8 . 2000 . 11032395 . 10.1089/10799900050151021 .
• DNA sequence and analysis of human chromosome 9 . Nature . 429 . 6990 . 369–74 . 2004 . 15164053 . 10.1038/nature02465 . 2734081 . Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE, Howe KL, Andrews TD . 2004Natur.429..369H.
• Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes . Pediatr. Infect. Dis. J. . 28 . 4 . 333–5 . 2009 . 19258923 . Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R . 10.1097/INF.0b013e31818e2aa9 . 25601837 . free .
• Hardy MP . Characterization of the type I interferon locus and identification of novel genes . Genomics . 84 . 2 . 331–45 . 2004 . 15233997 . 10.1016/j.ygeno.2004.03.003 . Owczarek CM . Jermiin LS . Ejdebäck . Mikael . Hertzog . Paul J. .
• Silva LK . Dengue hemorrhagic fever is associated with polymorphisms in JAK1 . Eur. J. Hum. Genet. . 18 . 11 . 1221–7 . 2010 . 20588308 . 10.1038/ejhg.2010.98 . 2950898 . Blanton RE . Parrado AR . Melo . Paulo S . Morato . Vanessa G . Reis . Eliana AG . Dias . Juarez P . Castro . Jesuina M . Vasconcelos . Pedro FC.
• Janssen R . Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes . J. Infect. Dis. . 196 . 6 . 826–34 . 2007 . 17703412 . 10.1086/520886 . Bont L . Siezen CL . Hodemaekers . Hennie M. . Ermers . Marieke J. . Doornbos . Gerda . Slot . Ruben van ’t . Wijmenga . Ciska . Goeman . Jelle J. . free .
• Shuai K . Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions . Cell . 76 . 5 . 821–8 . 1994 . 7510216 . 10.1016/0092-8674(94)90357-3 . Horvath CM . Huang LH . Qureshi . SA . Cowburn . D . Darnell Jr . JE . 41612814 .
• Gerhard DS . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . Wagner L . Feingold EA . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R.
• Sen GC, Lengyel P . The interferon system. A bird's eye view of its biochemistry . J. Biol. Chem. . 267 . 8 . 5017–20 . 1992 . 10.1016/S0021-9258(18)42719-6 . 1371992 . free .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2002 . 12477932 . 10.1073/pnas.242603899 . 139241 . Feingold EA . Grouse LH . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD. 2002PNAS...9916899M . free .
• Tiefenbrun N . Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest . Mol. Cell. Biol. . 16 . 7 . 3934–44 . 1996 . 8668211 . 10.1128/MCB.16.7.3934. 231390 . Melamed D . Levy N . Resnitzky . D . Hoffman . I . Reed . SI . Kimchi . A.
• Nagata S, Mantei N, Weissmann C . The structure of one of the eight or more distinct chromosomal genes for human interferon-alpha . Nature . 287 . 5781 . 401–8 . 1980 . 6159536 . 10.1038/287401a0. 1980Natur.287..401N . 29500779 .
• Todokoro K, Kioussis D, Weissmann C . Two non-allelic human interferon alpha genes with identical coding regions . EMBO J. . 3 . 8 . 1809–12 . 1984 . 6479148 . 10.1002/j.1460-2075.1984.tb02050.x. 557600.
• Schuurhof A . Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls . Pediatr. Pulmonol. . 45 . 6 . 608–13 . 2010 . 20503287 . 10.1002/ppul.21229 . Bont L . Siezen CL . Hodemaekers . Hennie . Van Houwelingen . Hans C. . Kimman . Tjeerd G. . Hoebee . Barbara . Kimpen . Jan L. L. . Janssen . Riny . 24678182 .

IFNA13 is an interferon gene.

Notes and References

1. Web site: Entrez Gene: interferon.
2. Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO . Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia . Genomics . 14 . 2 . 437–43 . October 1992 . 1385305 . 10.1016/S0888-7543(05)80238-1.