IFL (chemotherapy) explained

IFL
Specialty:	oncology

IFL is a chemotherapy regimen for treatment of certain cancers, consisting of concurrent treatment with irinotecan, leucovorin (folinic acid), and fluorouracil.^[1]

It is similar to the FOLFIRI regimen and uses the same drugs. However, the fluorouracil component is given as a bolus injection rather than as an infusion over 48 hours.

See also

• Dose-dense chemotherapy
• FOLFIRI
• FOLFOX
• FOLFIRINOX

Notes and References

1. Efficacy and safety of addition of bevacizumab to FOLFIRI or irinotecan/bolus 5-FU/LV (IFL) in patients with metastatic colorectal cancer: A meta-analysis. Medicine. 95. 46. e5221. 27861344. 5120901. 2016. Chen. K. Gong. Y. Zhang. Q. Shen. Y. Zhou. T. 10.1097/MD.0000000000005221.