IDEAL framework explained

IDEAL (Idea, Development, Exploration, Assessment, Long-term study) is a framework for describing the stages of innovation in surgery and other interventional procedures. The purpose of IDEAL is to improve the quality of research in surgery by emphasizing appropriate methods, transparency of data and rigorous reporting of outcomes.

To achieve this, the IDEAL framework provides a set of recommendations for improving the evidence base from research at each stage of innovation, as outlined in the seminal paper published in The Lancet in 2009.[1] The recommendations emphasize evaluating new procedures prospectively, entering patients and studies into registries and databases to capture all incidences of a procedure, and reporting outcomes by established protocols. It is the first and only such framework for evidence-based practice that was established specifically for surgery and interventional procedures.

Background

The IDEAL framework was the result of an expert consensus developed from a series of meetings held at Balliol College, Oxford, from 2007 to 2009. This group was known as the Balliol Collaboration. The purpose of the meetings was to address the challenges unique to establishing the optimal evidence base in surgery, including practical, methodological, and ethical challenges. Attendees to the meeting (the “IDEAL collaboration”) included experts in evidence-based medicine, including Cochrane Collaboration founder Iain Chalmers, public health expert Muir Gray, statistician and founder of the Centre for Statistics in Medicine in Oxford Doug Altman, clinician-researchers, methodologists, and manufacturers of medical devices.

Framework and recommendations

The five stages of IDEAL, and the recommendations for each stage, are as follows:

Stage 1: Idea

Stage 2a: Development

Stage 2b: Exploration

Stage 3: Assessment

Stage 4: Long-term study

Proposals

In the original publication in The Lancet, the authors outline a number of proposals for key stakeholders in the generation of surgical evidence. These include journal editors, funders of services and research, regulators, and professional societies.[2]

IDEAL collaboration

The original IDEAL collaboration consists of attendees to the Balliol meetings. Subsequent members include other stakeholders in evidence-based surgery and interventional procedures. The IDEAL collaboration is led by Oxford surgeon-researcher Peter McCulloch.[3]

Role in device regulation

While the initial Balliol meetings were intended to address innovations in surgery and interventional procedures, it soon became clear that there were also deficits in the evaluation of medical devices and implants used in such procedures. In December 2011, the Center for Devices and Radiological Health of the United States Food and Drug Administration held a public workshop on using the IDEAL framework to help develop high-quality evidence for devices and implants.[4] In September 2012, the FDA published its strategy for improved postmarket surveillance based in part on the discussions from the IDEAL meeting, including the promotion of registries for devices, better assessment of evidence already published, and improved reporting of adverse events.[5] IDEAL collaborators have written several editorials and commentaries in journals such as the British Medical Journal and The Lancet concerning the regulation of devices.[6] [7] [8]

External links

Notes and References

  1. McCulloch P, Altman DG et al. "No surgical innovation without evaluation: the IDEAL recommendations." Lancet. 2009 Sep 26;374(9695):1105-12. doi: 10.1016/S0140-6736(09)61116-8.
  2. Web site: IDEAL Proposals for actions which would improve the environment for invasive therapy research. IDEAL. 17 February 2014. 19 March 2017. https://web.archive.org/web/20170319004256/http://www.ideal-collaboration.net/proposals/. dead.
  3. http://www.nds.ox.ac.uk/about-nds/staff-listing/peter-mcculloch Peter McCulloch — Nuffield Department of Surgical Sciences
  4. Web site: Transcript for Public Workshop - Bridging the IDEAL and TPLC Approaches for Evidence Development for Surgical Medical Devices and Procedures. fda.gov. U.S. Food and Drugs Administration. 17 February 2014. December 2, 2011.
  5. Web site: Strengthening Our National System for Medical Device Postmarket Surveillance. fda.gov. U.S. Food and Drug Administration. 17 February 2014. September 2012.
  6. McCulloch P. "The EU's system for regulating medical devices." BMJ. 2012 Oct 24;345:e7126. doi: 10.1136/bmj.e7126.
  7. "McCulloch P, Barkun J, Sedrakyan A; IDEAL Collaboration. "Implantable device regulation in Europe." Lancet. 2012 Aug 25;380(9843):729. doi: 10.1016/S0140-6736(12)61405-6.
  8. McCulloch P. "Wanted: an appropriate evaluation template." BMJ. 2011 Jun 7;342:d3540. doi: 10.1136/bmj.d3540.