Hydroxymethyl group explained

The hydroxymethyl group is a substituent with the structural formula . It consists of a methylene bridge (unit) bonded to a hydroxyl group . This makes the hydroxymethyl group an alcohol. It has the identical chemical formula with the methoxy group that differs only in the attachment site and orientation to the rest of the molecule. However, their chemical properties are different.[1] [2]

Hydroxymethyl is the side chain of encoded amino acid serine.[3]

Notes and References

  1. Book: NAMING ORGANIC COMPOUNDS . dead . 37 . https://web.archive.org/web/20220721055000/https://www.kpu.ca/sites/default/files/downloads/sup08.pdf . 2022-07-21 . 2022-08-08.
  2. Dong . Hao . Zheng . Erjin . Niu . Zhiyin . Zhang . Xiaoyu . Lin . Yi-Yu . Jain . Priyesh . Yu . Qiuming . 2020-04-15 . Hydroxymethyl-Functionalized PEDOT-MeOH:PSS for Perovskite Solar Cells . live . ACS Applied Materials & Interfaces . 12 . 15 . 17571–17582 . 10.1021/acsami.0c01756 . 1944-8252 . 32204591 . 214630308 . https://web.archive.org/web/20220808221741/https://pubmed.ncbi.nlm.nih.gov/32204591/ . 2022-08-08 . 2022-08-08.
  3. Perczel . András . Farkas . Ödön . Csizmadia . Imre G. . 1996-01-01 . Peptide Models. 18. Hydroxymethyl Side-Chain Induced Backbone Conformational Shifts of l -Serine Amide. All ab Initio Conformers of For- l -Ser-NH 2 . live . Journal of the American Chemical Society . en . 118 . 33 . 7809–7817 . 10.1021/ja960464q . 0002-7863 . https://web.archive.org/web/20220808210908/https://pubs.acs.org/doi/10.1021/ja960464q . 2022-08-08 . 2022-08-08.

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