Hydroxycarteolol Explained
Iupac Name: | 8-Hydroxy-5--3,4-dihydro-2(1H)-quinolinone |
Cas Number: | 59826-22-1 |
Atc Prefix: | None |
Pubchem: | 124688 |
Chemspiderid: | 111020 |
Chebi: | 192312 |
Synonyms: | 8-Hydroxycarteolol |
C: | 16 |
H: | 24 |
N: | 2 |
O: | 4 |
Smiles: | O=C2Nc1c(O)ccc(OCC(O)CNC(C)(C)C)c1CC2 |
Stdinchi: | 1S/C16H24N2O4/c1-16(2,3)17-8-10(19)9-22-13-6-5-12(20)15-11(13)4-7-14(21)18-15/h5-6,10,17,19-20H,4,7-9H2,1-3H3,(H,18,21) |
Stdinchikey: | TVZJLAKRXHGVOK-UHFFFAOYSA-N |
Hydroxycarteolol is a beta blocker and metabolite of carteolol.[1] [2]
Notes and References
- A comparison of the opacifying effects of carteolol.HCl and 8-hydroxycarteolol.HCl in the isolated porcine cornea . Igarashi H, Katsuta Y, Sawa K, Nakazato Y, Kawasaki T . Fundam Appl Toxicol . Apr 1990 . 14 . 3 . 554ā559 . 2340982 . 10.1093/toxsci/14.3.554.
- The beta-adrenoceptor antagonist carteolol and its metabolite 8-hydroxycarteolol have different intrinsic sympathomimetic activities . Jasper JR, Michel MC, Insel PA . Br J Clin Pharmacol . 1990 . 30 . Suppl 1 . 109Sā111S . 2176514 . 1368107 . 10.1111/j.1365-2125.1990.tb05477.x.