Hydroxycarteolol Explained

Iupac Name:8-Hydroxy-5--3,4-dihydro-2(1H)-quinolinone
Cas Number:59826-22-1
Atc Prefix:None
Pubchem:124688
Chemspiderid:111020
Chebi:192312
Synonyms:8-Hydroxycarteolol
C:16
H:24
N:2
O:4
Smiles:O=C2Nc1c(O)ccc(OCC(O)CNC(C)(C)C)c1CC2
Stdinchi:1S/C16H24N2O4/c1-16(2,3)17-8-10(19)9-22-13-6-5-12(20)15-11(13)4-7-14(21)18-15/h5-6,10,17,19-20H,4,7-9H2,1-3H3,(H,18,21)
Stdinchikey:TVZJLAKRXHGVOK-UHFFFAOYSA-N

Hydroxycarteolol is a beta blocker and metabolite of carteolol.[1] [2]

Notes and References

  1. A comparison of the opacifying effects of carteolol.HCl and 8-hydroxycarteolol.HCl in the isolated porcine cornea . Igarashi H, Katsuta Y, Sawa K, Nakazato Y, Kawasaki T . Fundam Appl Toxicol . Apr 1990 . 14 . 3 . 554ā€“559 . 2340982 . 10.1093/toxsci/14.3.554.
  2. The beta-adrenoceptor antagonist carteolol and its metabolite 8-hydroxycarteolol have different intrinsic sympathomimetic activities . Jasper JR, Michel MC, Insel PA . Br J Clin Pharmacol . 1990 . 30 . Suppl 1 . 109Sā€“111S . 2176514 . 1368107 . 10.1111/j.1365-2125.1990.tb05477.x.