Hydrocortisone sodium succinate explained

Tradename:Solu-Cortef
Dailymedid:Hydrocortisone sodium succinate
Routes Of Administration:Intravenous, intramuscular
Class:Corticosteroid
Glucocorticoid
Atc Prefix:A01
Atc Suffix:AC03
Legal Au:S4
Legal Au Comment:[1]
Legal Us:Rx-only
Legal Us Comment:[2]
Cas Number:125-04-2
Pubchem:23694214
Drugbank:DBSALT001297
Chemspiderid:390144
Unii:50LQB69S1Z
Kegg:D00978
Chebi:5782
Chembl:1200495
Iupac Name:Sodium 4-[2-[(8''S'',9''S'',10''R'',11''S'',13''S'',14''S'',17''R'')-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1''H''-cyclopenta[''a'']phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoate
C:25
H:34
O:8
Na:1
Smiles:C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)COC(=O)CCC(=O)[O-])O)C)O.[Na+]
Stdinchi:1S/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1
Stdinchikey:HHZQLQREDATOBM-CODXZCKSSA-M

Hydrocortisone sodium succinate, sold under the brand name Solu-Cortef among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.[3]

Hydrocortisone sodium succinate was approved for medical use in the United States in 1955.

Notes and References

  1. Web site: CIPLA HYDROCORTISONE, CORTI-H, CORTICIP, HYDROCIP (Cipla Australia Pty Ltd) . . https://web.archive.org/web/20230318074302/https://www.tga.gov.au/resources/prescription-medicines-registrations/cipla-hydrocortisone-corti-h-corticip-hydrocip-cipla-australia-pty-ltd . 2023-03-18 . live.
  2. Web site: Solu-Cortef- hydrocortisone sodium succinate injection, powder, for solution . DailyMed . 19 August 2021 . 23 December 2023.
  3. Book: Brownell CL, Priff N . Nursing2009 Student Drug Handbook . 2009 . Wolters Kluwer . Philadelphia . 978-0-7817-8883-0 . 642 . 10th . Hydrocortisone . https://books.google.com/books?id=Btu3fi17c10C&dq=Hydrocortisone+sodium+succinate&pg=PA642.