Hyclate Explained

A hyclate (la|hyclas) is a pharmaceutical term for hydrochloride hemiethanolate hemihydrate[1] [2] (·HCl·EtOH·H2O), e.g. doxycycline hyclate.[3] [4]

Notes and References

  1. Web site: hyclate . The Free Dictionary . 5 June 2018.
  2. Legendre . Alexandre O. . Silva . Laila R. R. . Silva . Douglas M. . Rosa . Iara M. L. . Azarias . Lilian C. . de Abreu . Polyana J. . de Araújo . Magali B. . Neves . Person P. . Torres . Claudia . Martins . Felipe T. . Doriguetto . Antonio C. . Solid state chemistry of the antibiotic doxycycline: structure of the neutral monohydrate and insights into its poor water solubility . CrystEngComm . 2012 . 14 . 7 . 2532–2540 . 10.1039/C1CE06181J .
  3. Web site: Doxycycline hyclate – Final text to replace published monograph in The International Pharmacopoeia . who.int . 5 June 2018.
  4. Note: As of June 2018, doxycycline hyclate is apparently the only known, or used hyclate.

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