Hybrid oncocytoma/chromophobe renal cell carcinoma explained

Specialty:Oncology/Nephrology

Hybrid oncocytoma/chromophobe renal cell carcinoma is rare subtype of renal cell carcinoma.[1] It arises from intercalated cells of cortical collecting ducts of the kidney.It is associated with extreme hypodiploidy with multiple losses of entire chromosomes 1, 2, 6, 10, 13, 17, 21 and Y.

Notes and References

  1. Ruiz-Cordero . Roberto . Rao . Priya . Li . Lerong . Qi . Yuan . Atherton . Daniel . Peng . Bo . Singh . Rajesh R. . Kim . Tae-Beom . Kawakami . Fumi . Routbort . Mark J. . Alouch . Nail . Chow . Chi-Wan B. . Tang . Ximing . Lu . Wei . Brimo . Fadi . Matin . Surena F. . Wood . Christopher G. . Tannir . Nizar M. . Wistuba . Ignacio I. . Chen . Ken . Wang . Jing . Medeiros . L. Jeffrey . Karam . Jose A. . Tamboli . Pheroze . Sircar . Kanishka . Hybrid oncocytic/chromophobe renal tumors are molecularly distinct from oncocytoma and chromophobe renal cell carcinoma . Modern Pathology . November 2019 . 32 . 11 . 1698–1707 . 10.1038/s41379-019-0304-y . en . 1530-0285. free .

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