| Hüseyin Avni | |
| Honorific-Suffix: | Pasha |
| Office1: | Grand Vizier of the Ottoman Empire |
| Birth Date: | 1820 |
| Birth Place: | Isparta, Anatolia Eyalet, Ottoman Empire |
| Death Place: | Istanbul, Ottoman Empire |
Hüseyin Avni Pasha (1820 – 15 June 1876) was an Ottoman governor-general and statesman.[1] He was Grand Vizier of the Ottoman Empire from 15 February 1874 to 26 April 1875. He was killed by Çerkez Hassan[2] the younger brother of Neşerek Kadın Efendi, who accused him of the murder of Ottoman Sultan Abdülaziz, on 15 June 1876 during a cabinet meeting of Ottoman Sultan Murad V at the residence of Midhat Pasha near Beyazıt in Fatih, Istanbul. The foreign affairs minister Mehmed Rashid Pasha was also killed in the attack.